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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
enogene/Rapamycin/0.1mg/E1B1842
产品编号:E1B1842
市  场 价:¥1200.00
场      地:美国(厂家直采)
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$60.00
品      牌: enogene
公      司:enogene
公司分类:
enogene/Rapamycin/0.1mg/E1B1842
商品介绍

RapamycinPDF

  • Catalog Number:

    E1B1842
  • Amount:

    0.1mg
  • PHYSICAL APPEARANCE: Off-white or yellow solidMOLECULAR FORMULA: C51H79NO13

  • Molecular Weight:

    914.2
  • Purity:

    98% (TLC: 10% MeOH/Methylene chloride; Rf = 0.51)
  • Storage/Stability:

    Store solutions at -20°C for up to 1 year.
  • Recommended Dilutions:

    Binds to and inhibits the FK506 binding protein (FKBP) proline rotamase. Rapamycin is bound simultaneously by FKBP12 and FRAP (FKBP12-Rapamycin-Associated-Protein). Rapamycin/FKBP complex does not inhibit FRAP PI 4-kinase activity, but does inhibit FRAP autophosphorylation. Rapamycin is unique in its ability to inhibit lymphokine induced cell proliferation at the G1 to S phase. Rapamycin selectively blocks signaling leading to the activation of p70/85 S6 kinase.
  • References:

    1. J.Y.Chang et al. Trends Pharmacol.Sci. 1991 12 2182. J.Choi et al. Science 1996 273 1833. D.M.Sabatini et al. J.Biol.Chem. 1995 270 208754. E.J.Brown et al. Nature 1995 377 4415. J.E.Kay et al. Immunology 1991 72 5446. W.G.Morice et al. J.Biol.Chem. 1993 268 37347. J.Heitman et al. Science 1991 253 9058. D.J.Price et al. Science 1992 257 9739. D.C.Fingar et al. J.Biol.Chem. 1993 268 300510. J.Chung et al. Cell 1992 69 1227The pharmacological and toxicological properties of this product have not been fully investigated. Exercise caution in use and handling. This product must not be used in humans.
  • Price:

    60$
  • Form of Antibody:

    RapamycinCAS NO: 53123-88-9

品牌介绍

enogene的PTEN(Phospho-Ser380)抗体PDF

目录编号:E011009-1

量:50微克/ 50微升

抗体形式:磷酸盐缓冲盐水(不含Mg2 +和Ca2 +),pH 7.4、150mM NaCl,0.02%叠氮化钠和50%甘油的兔IgG。

储存/稳定性:-20℃/ 1年保存

免疫原产生抗人丝氨酸380(RY-SP-DT)磷酸化位点周围人PTEN合成的磷酸肽的抗血清。

纯化:使用表位特异性磷酸肽通过亲和层析从兔抗血清中亲和纯化抗体。使用对应于磷酸化位点的非磷酸肽,通过色谱法除去针对非磷酸肽的抗体。

特异性/敏感性:PTEN(phospho-Ser380)抗体仅在丝氨酸380磷酸化时才检测PTEN的内源性水平。

反应性:人,小鼠,大鼠

应用范围:IHC:1:50〜1:100


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